South Dakota Code § 58-1-25

Use of genetic tests in offer, sale, or renewal of insurance prohibited
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No health carrier, life insurer, or long-term care insurer, in determining eligibility for coverage, establishing premiums, limiting coverage, renewing coverage, or any other underwriting decision, may, in connection with the offer, sale, or renewal of insurance:
(1) Require or request an individual or a blood relative of the individual to take a genetic test; or
(2) Take into consideration the fact that a genetic test was refused by an individual or a blood relative of the individual.

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