South Dakota Code § 10-46-15.5

Exemption of prescribed drugs used by humans
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The use in this state of drugs as defined by rule promulgated by the secretary of revenue pursuant to chapter
1-26
to the extent used by humans, if the drugs are prescribed by prescription, dispensed, or administered by a physician, chiropractor, optometrist, dentist, podiatrist, or audiologist, is specifically exempt from the tax imposed by this chapter.

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